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Specific Information

The Master Programme of Life Science Informatics is a two years course, accredited by ASIIN.

Structure of the Programme

The Master Programme of Life Science Informatics is made up of the following modules:
  • Computer Science (COS), 15 Credit Points (CP)
  • Life Science Research (LSR), 15 CP
  • Algorithmic Life Science Informatics (ALB), 15 CP
  • Modelling, Simulation, Statistics (MOD), 15 CP
  • Specialisation in Biology (BIO), 15 CP
  • Specialisation in Chemistry (CHM), 15 CP
Total yield of credit points earned in courses: 90 CP

Another 30 CP have to be acquired with the master thesis.

Total yield of CP earned in the master programme (courses and thesis): 120 CP

Students have the opportunity to either specialise in bioinformatics or in chemoinformatics.

The programme emphasizes the students' early exposure to eminent scientists. Therefore courses and Lecture Series with invited excellent researchers in their respective fields are offered to students to broaden their horizon.

One example on how this is achieved, is the LSI International Lecture Series. Students had the opportunity to discuss current topics from the field of Life Science Informatics with a plethora of highly experienced researchers.

Who should apply?

The focus of this programme is clearly set on computer science (programming, algorithmic concepts) and mathematics. These subjects will make up a substantial part of your studies and the chances to be admitted will strongly depend on the past performance in both disciplines from school on. If you are a life scientist and mathematics was not the favourite topic at university studies you should re-consider your application for this programme.

If you are a computer scientist or mathematician you should have a clear and dedicated interested in the life sciences. If biology or the life sciences were not the favourite topic at university studies you should re-consider your application for this programme.

The master programme of Life Science Informatics focuses on educating students to solve specific problems in the modern life sciences with methods and concepts from mathematics and computer science. This will include for instance programming, algorithmic concepts or mathematical approaches. A substantial interest in and a dedication to the life sciences is important in order to apply the aforementioned methods and concepts in a meaningful way.

Areas of Future Application

Which areas do exhibit a great need for Life Science Informatics graduates? Here are some examples:
  • Systems Biology
  • Personalised Medicine
  • Personalised Healthcare
  • Virtual Physiologcal Human
  • Computer-aided Drugn Design
  • Molecular Modelling
  • Medical Informatics

Some Employers of Life Science Informatics Graduates

  • B-IT Research School, Aachen-Bonn, Germany
  • Cambridge University, United Kingdom
  • University of Oxford, United Kingdom
  • European Bioinformatics Institute, Cambridge, United Kingdom
  • Max Dellbrück Center Berlin, Germany
  • Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
  • Max Planck Institute for Plant Breeding Research, Cologne, Germany
  • Max Planck Institute for the Biology of Ageing, Cologne, Germany
  • Max Planck Institute Tübingen, Tübingen, Germany
  • Fraunhofer Institute SCAI, Sankt Augustin, Germany
  • German Center for Cancer Research (DKFZ) Heidelberg, Germany
  • Leaf Bioscience s.r.l., Milan, Italy
  • National Technical University of Singapore, Singapore
  • Philips Research
  • Research Center Jülich, Jülich, Germany
  • RWTH Aachen, Aachen Germany
  • University of Luxemburg, Luxembourg
  • University of Utrecht, The Netherlands
  • University of Tübingen, Germany
  • University of Cologne, Cologne, Germany
  • University of Bonn, Bonn, Germany
  • Galilleo Press, Bonn, Germany

Insight into the Current Programme

If you want to find out more about the currently running programme and the courses offered, please follow these links:

Timetable for the first semester: Timetable for the first semester (Winter Semester 2011/2012)
Timetable for the third semester: Timetable for the third semester (Winter Semester 2011/2012)

Timetable of Summer Semester 2011: Timetable for Summer Semester 2011

Some Topics of Masters Theses carried out in the Previous Years

  • Generation and Validation of a Semantic Framework describing Protein-ligand Interactions

  • Using Database Knowledge to estimate protein abundance in physiologically based pharmacokinetic modeling

  • Bioinformatic Approaches towards Genome wide Analysis of short RNAs in Craterostigma Plantagineum

  • Automatic Assignment of Human Readable Descriptions to Protein Sequences

  • Computational Characterization of Structure Activity Relationship Microenvironment in Compound and Screening Data Sets

  • Investigation of Algorithms for Context-Sensitive Detection of regulation Failures based on Features derived from the Electrocardiogram and Photo- Plethysmogram

  • Contribution of Docking to the Reconstruction of Protein Interaction Networks

  • Rationalizing Three-Dimensional Activity Landscapes and the Influence of Molecular Representations on Landscape Topology and the Formation of Activity Cliffs

  • Evaluation of Scaffold Mapping Potential in Similarity Searching

  • Indexing, Annotation and Visualisation System for Knowledge Discovery

  • Array Process: Work Flow for Microarrays

  • A Hardware and Software environment for observing and analysing long term Behaviour of embryonic stem cellderived Cardiomyocytes

  • Reanalyzing phylogenetic data of the Sacoglossa (Mollusca, Gastropoda, Opisthobranchia)

  • PDB Vs SWISS-PROT: The comparison of two protein databases

  • Bayesian Network Modeling for Cerebral Aneurysm Rupture Risk and Treatment

  • Strategies for the generation of higher order protein dictionaries for text-mining: Complex and family name dictionaries

  • Genomic Analysis of the Primary Metabolism of the uncultivated Symbiont ”Pseudomonas paederi”

  • Test of Reliability and Efficiency of two Middlewares through Application of two large scale Docking Tools

  • Clustering of Gene Expression Time Series

  • Databases as training sets for machine learning: Assessing optimal chemical space coverage

  • Performance Analysis of Selected Molecular Similarity Methods on Compound Activity Classes of Increasing Structural Diversity

  • Conceptual Design of a Protocol Database for Chemical Image Mining

  • Development of a Descriptor Histogram Filtering Method for Compound Database Mining

  • An Application of Data Mining Methods in Chemical Compounds’ Classification and Regression Problems

  • Large-Scale Virtual High Throughput Screening (vHTS) on an Optical High-Speed Testbed

  • Extension of chemoCR: From reconstruction of chemical molecules to reconstruction of whole chemical reactions

  • Characterisation of voltage-gated Ion Channels in human stem cell-derived Neurons

  • Optimizing Combinations of Random Molecular Fragments for Similarity Searching by Frequency Analysis

  • Modelling of Genome-Scale Metabolic Networks: Data Acquisition and Networks

  • Concept-based Semi-Automatic Extension of Drug Hierarchies

  • Structure-activity Relationships and Pharmacophor Modelling of Purine Receptor Antagonists.

  • Enhancing Methods for the Biomedical Knowledge Discovery Process

  • The Relationship Between Genetic Redundancy and Correlated Expression of Duplicated Genes in A. thaliana and C. elegans

  • Modelling and Analysis of Scorpion Walking Patterns for Posterior and Anterior Leg

  • Kinetic and docking Studies on the Interaction of Proteases with Molecular Weight Compounds

  • Global Analysis of Genes expressed during Mesodermal Development (Microarray Data Analysis-Affymetrix data)

  • Network-based Approach for Analyzing Pathway Interactions

  • Visualization and Analysis of Multi-Modal extracted Information from Full Text and Patent Corpora

  • PaperMaker: Consistency Analysis of Scientific Biomedical Literature

  • Modelling of Genome-Scale Metabolic Networks: Data Acquisition and Simulation Process

  • Concept-Based Semi-Automatic Extension of Drug Hierarchies

  • Integration of Data Resources for Knowledge Discovery in Life Science

    List of Research Partners

    Some of the theses mentioned above were carried out in collaboration with research partners outside B-IT and B-IT constituting partners. Some examples of such research collaborations are:

  • European Bioinformatics Institute
  • ETH Zürich
  • Research Center Juelich (Forschungszentrum Jülich)
  • Max Planck Institute for Plant Breeding Research Cologne
  • Bayer Technology Services
  • Cubic (Cologne University Bioinformatics Center)
  • University of Cologne

    Admission

    For specific conditions of admission for international applicants please check our Online-Application.

    For more information please contact

    B-IT
    Coordination Team of
    Life Science Informatics
    Dahlmannstraße 2
    D-53113 Bonn
    Germany
    E-mail: msc-lsi (at) b-it-center.de*

    *Note: Please replace "(at)" with "@" and remove the blanks to get the correct e-mail address.

    Last update: 19 July 2011
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